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Clinical Pharmacology

Adverse Drug Reactions

	Adverse Drug Reactions
			Etiology
			Symptoms and Signs
			Diagnosis
			Treatment
			Prevention

Concepts in Pharmacotherapy

	Introduction
	Adherence to a Drug Regimen
	Drug Development
	Drug Errors
	Drug Interactions
				Minimizing drug interactions
	Pharmacogenetics
				Malignant hyperthermia
	Placebos
				Effects
				Uses

Drug Therapy in the Elderly

	Introduction
	Adverse Drug Effects in the Elderly
	Considerations for Effective Drug Therapy in the Elderly
	Drug Categories of Concern in the Elderly
				Analgesics
				Anticoagulants
				Antihypertensives
				Antiparkinsonian drugs
				Digoxin
				Diuretics
				Antihyperglycemics
				Psychoactive drugs
	Pharmacodynamics in the Elderly
	Pharmacokinetics in the Elderly
				Absorption
				Distribution
				Hepatic metabolism
				Renal elimination

Pharmacodynamics

	Introduction
	Chemical Interactions
	Dose-Response Relationships
	Drug-Receptor Interactions
				Agonists and antagonists

Pharmacokinetics

	Introduction
	Absorption
				Passive diffusion
				Facilitated passive diffusion
				Active transport
				Pinocytosis
		Oral Administration
		Parenteral Administration
		Controlled-Release Forms
	Bioavailability
				Causes of low bioavailability
				Assessing bioavailability
	Distribution
				Volume of distribution
				Binding
				Blood-brain barrier
	Excretion
				Renal excretion
				Biliary excretion
	Metabolism

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